zebrafish and brain repair

Filed under: healthy living,insomnia,sleep — Tags: , , — Orna @ 1:58 pm

Healthy brains require healthy sleep.


Really, you can’t fudge on this. At least not for long.


This cool study looked at zebrafish (fun in itself.) The researchers determined that normal wakefulness caused damage to DNA in nervous system cells. That makes sense; life involves wear and tear.


The interesting finding, though, was that sleep turned on the zebrafishes’ DNA repair mechanisms. Those mechanisms were less active during daytime, when the damage was occurring.


Scientists are still figuring out how all the pieces work together. But from a daily human perspective it makes the same kind of sense as repairing major highways at night: Get the work done while traffic is low.


Potholes on the highway are tough on your car and diminish its useful life. The same is true for potholes in our brains’ DNA — but replacements are harder to come by.


So, sleep.


How much sleep is enough? Zebrafish can’t tell us what humans need. But generally speaking, anything less than seven hours per night diminishes our ability to function crisply.


Want to get your best sleep? Check out my FREE Sound Sleep Cheat Sheet.


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Citation: Zada D, Bornshtein I, Lerer-Goldshtein T, Garini Y, Applebaum L. Sleep increases chromosome dynamics to enable reduction of accumulating DNA damage in single neurons. Nature Communications. 2019;10:895

P.S. What’s a zebrafish? This:


sleep | dr. orna izakson | sleep to repair DNA

Zebrafish need sleep to repair their nervous systems. So do you.

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